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KMID : 0363219950330050956
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Korean Journal of Dermatology
1995 Volume.33 No. 5 p.956 ~ p.960
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A Case of Diffuse Extensive Metastatic Carcinoma Showing Unusual Clinical Features
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신문석
권호준/류영욱/정재봉/김병천/이규석
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Abstract
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Cutaneous metastases from Internal carcinomas are relatively rare.
We report a case of cutaneous metastasis believed to originate from primary lung carcinoma in a 69-year-old male patient. The patient presented with localized well defined multiple variable sized, hard erythematous papules, nodules and pustules
on
the
right chest, back and upper arm.
Biopsy specimens from the nodules upper chest revealed scattered islands of tumor cells and fibrosis of the dermis.
To evaluate the role of p53 protein in the development of skin tumors, we examed p53 expression at protein level by immunoperoxidase stain using monoclonal antimouse human p53 antibody on paraffin embeded tissues.
The patient died after four months from the appearance of cutaneous lesions. (Kor J Dermatol 1995;33(5) : 956~960)
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KEYWORD
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